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Biotech Reverse Mergers
Precedent Deal Activity Tracker

A maintained database of biopharma reverse merger transactions — structures, timelines, PIPE mechanics, and ownership outcomes. Updated as deals are announced and closed.

62
Deals tracked
20
Active / Pending
52
With PIPE financing
2023–26
Coverage period

Most recent: Velaris Therapeutics / Alaunos Therapeutics (TCRT), announced Oct 2026, $350.0mm PIPE.

Tracking 62 biopharma reverse merger transactions announced 2023–2026, sourced to merger agreement defined terms (Exhibit 2.1 / 8-K filings).

20 deals currently active or pending; 52 include PIPE financing alongside the reverse merger.

Process Guide

Two Paths to Public: Structure Comparison

Sign & Close

Tender Offer / Consent Solicitation
2–4 weeks
Schedule 14f-1 + Super 8-K
Reg D / 4(a)(2) — restricted
None (written consent)

    Advantages

  • Speed — weeks, not months
  • Price / consideration certainty
  • Lower transaction costs
  • Ideal for shells with runway urgency

    Risks

  • Compressed diligence window
  • Shareholder litigation risk
  • Nasdaq continued listing pressure
  • No fiduciary-out protection

Traditional RM

Sign → SEC Review → Proxy → Shareholder Vote → Close
4–6 months
Form S-4 + Proxy Statement
Form S-4 — freely tradable
Required

    Advantages

  • Full diligence period
  • Clean governance via shareholder vote
  • Preferred by target boards
  • Fiduciary safe harbor

    Risks

  • Market exposure over 4–6 months
  • SEC comment cycle unpredictability
  • Vote failure risk
  • Go-shop / fiduciary-out exposure
Search
Year
Structure
Year ↕ Acquirer (PrivateCo) ↕ Target (PubCo Shell) ↕ Announced ↕ Closed ↕ PIPE / Financing ↕ Acquirer % PIPE % Shell % Net Cash ↕ Listing Prem ↕ Structure ↕ Notes
2023
CalciMedica, Inc.
Model this deal →
Graybug Vision, Inc. (GRAY)
CALC
Nov 2022 Mar 2023 $10.3mm 64.0% 7.4% 28.6% $25.0M $15.0M Traditional CalciMedica $100mm total valuation (incl. PIPE) vs. Graybug $40mm. Net cash peg $25mm target, $18mm closing floor. 14:1 reverse split. PIPE investors not named (accredited investors under an SPA).
2023
Redx Pharma
Model this deal →
Jounce Therapeutics (JNCE)
JNCE
Feb 2023 None (all-stock combination) 63% NA 37% ~$130.0M NA Terminated Originally announced Feb 23, 2023: all-stock combination, Redx ~63% / Jounce ~37%, ~$130M cash post-transaction. Terminated Mar 2023 when Jounce instead accepted a superior cash tender offer from Concentra Biosciences.
2023
Neurogene
Model this deal →
Neoleukin Therapeutics
NGNE
Jul 2023 Dec 2023 $95.0mm (Great Point, EcoR1, Redmile, Samsara, Janus, BlackRock, Casdin, Avidity, Arrowmark, Cormorant, Alexandria) 57% 27% 16% ~$66.0M ~($10.0M) Traditional
CVR
Neoleukin shareholders got 1 non-transferable CVR each for asset sales, lease savings, tax refunds; expires Jun 30, 2029
2023
Serina Therapeutics
AgeX Therapeutics
SER
Aug 2023 Mar 2024 None 75% NA 25% ND ND Traditional Juvenescence warrants ~$15.0mm plus debt reduction; no PIPE.
2023
Q32 Bio
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Homology Medicines (FIXX)
QTTB
Nov 2023 Mar 2024 $42.0mm (OrbiMed, Atlas, Abingworth, BMS, Sanofi) 61.0% 13.4% 25.6% $60.0M ~$20.0M Traditional
CVR
Homology shareholders got CVRs for HMI-103, HMI-204, capsids/AAVHSC platform, OXB LLC equity; payments completed Q2 2025. PIPE priced at $8.00/sh.
2024
Tectonic Therapeutic
Model this deal →
Avrobio (AVRO)
TECX
Feb 2024 Jun 2024 $130.7mm 40.2% 37.5% 22.3% ~$65.0M ~$10.0M Traditional
CVR
AVROBIO shareholders got 1 non-transferable CVR/share for proceeds from legacy assets (gene therapy, lentiviral platform). PIPE = $96.6mm subscription + $34.1mm SAFE conversion.
2024
Peak Bio
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Akari Therapeutics
AKTX
Mar 2024 Oct 2024 ~$10.0mm 48% ND 52% NA NA SPAC/Other Plus a $3.2mm additional placement.
2024
Oruka Therapeutics
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ARCA biopharma (ABIO)
ORKA
Apr 2024 Sep 2024 $275.0mm (Venrock, RTW, Access Biotech) 38.0% 59.7% 2.4% $5.0M $6.0M Traditional
Cash Div
YES — $20M cash dividend to ARCA shareholders from ARCA cash reserves pre-close
2024
Trawsfynydd Therapeutics
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Onconova Therapeutics (ONTX)
TRAW
Apr 2024 Apr 2024 $14.0mm (OrbiMed, Torrey Pines) 75.7% 10.6% 13.7% ND ND Sign & Close
CVR
All-stock merger; combined co. renamed Traws Pharma (TRAW). Onconova (shell) legacy holders receive a CVR tied to narazaciclib and rigosertib proceeds.
2024
TuHURA Biosciences
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Kintara Therapeutics (KTRA)
HURA
Apr 2024 Oct 2024 None (all-stock reverse recap) 97.15% NA 2.85% ND ND Sign & Close
CVR
Kintara shareholders got CVRs tied to clinical milestones
2024
Flerie Invest AB
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InDex Pharmaceuticals (Nasdaq First North)
INDEX
May 2024 Jun 2024 ~$48.0mm (AP4, HBM, Linc) 91.9% ND 8.1% ~$21.0M ~$4.0M Traditional Financing was a SEK 520mm directed share issue.
2024
OnKure Therapeutics
Model this deal →
Reneo Pharmaceuticals (RPHM)
OKUR
May 2024 Oct 2024 $65.0mm (Acorn, Cormorant, Deep Track, Perceptive, Samsara, Surveyor (Citadel), Vestal Point) 53.6% 21.3% 25.1% $61.0M ~$14.0M Traditional —
2024
Ceapro
Aeterna Zentaris (AEZS)
CSCI
Jun 2024 Jun 2024 None (all-stock; warrants issued) 50% NA 50% NA NA SPAC/Other —
2024
Crescent Biopharma
Model this deal →
GlycoMimetics (GLYC)
CBIO
Oct 2024 Jun 2025 $200.0mm (Fairmount, Venrock, BVF) 96.9% ND 3.1% $1.8M ~$6.2M Sign & Close —
2024
Journey Therapeutics
Entero Therapeutics
JOUR
Nov 2024 NA NA NA NA NA NA Terminated Entero abandoned the Journey merger; instead acquired an unrelated company (GRID AI, AI/data-center) around Oct 2025. Deal required a $5.0mm equity financing; terminated before it was raised.
2024
Kalaris Therapeutics
Model this deal →
AlloVir (ALVR)
KLRS
Nov 2024 Mar 2025 None (all-stock) 74.5% NA 25.5% $100.0M ~$16.0M Sign & Close ~$100.0mm cash post-close.
2024
Lomond Therapeutics
Model this deal →
Venetian-1 Acquisition Corp.
ND
Nov 2024 Nov 2024 $32.9mm (OrbiMed, Torrey Pines, Deerfield, American Financial Group, Heights) 60.0% 34.3% 5.7% NA NA Sign & Close Venetian-1 was a private Form 10 blank-check shell, not a listed/trust SPAC -- it never IPO'd and explicitly stated it would not seek a public market until after a merger. No confirmed active ticker since. First PIPE closing of 8,241,375 sh at $4.00; up to $16.1mm more authorized through Nov 30, 2024 (widely reported as $44.0mm total).
2024
Renexxion
Relief Therapeutics (RLF)
RLF
Nov 2024 ND (Renexxion planned concurrent private financing, terms undisclosed) 72.2% ND 27.8% ND ND Terminated Originally announced Nov 4, 2024 (non-binding LOI): Renexxion equity valued at $260M (~72.2% ownership), Relief equity valued at $100M (~27.8%). Terminated Mar 6, 2025 -- key closing conditions not met within required timeframe.
2024
Inmagene Biopharm
Model this deal →
Ikena Oncology (IKNA)
IMA
Dec 2024 Jul 2025 $75.0mm (Deep Track, Foresite, RTW; existing Ikena holders: BVF, Blue Owl, Omega, OrbiMed) 43.1% 21.6% 35.3% ~$100.0M ~$20.0M Traditional
CVR
Non-transferable CVRs for legacy pipeline assets (both groups)
2025
Decoy Therapeutics
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Salarius Pharmaceuticals (SLRX)
DCOY
Jan 2025 Nov 2025 ~$7.0–$8.0mm 92.4% ND 7.6% NA NA Sign & Close Financing is the 'Qualified Financing' under the merger agreement.
2025
Betaliq
Eyenovia (EYEN)
EYEN
Mar 2025 None (LOI stage, all-stock) 83.7% NA 16.3% NA NA LOI Only Exclusivity period lapsed May 16, 2025 without a definitive agreement; Eyenovia later rebranded entirely as Hyperion DeFi (crypto/DeFi pivot) in July 2025.
2025
Pelthos Therapeutics
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Channel Therapeutics (CHRO)
PTHS
Apr 2025 Jul 2025 $50.1mm (Ligand led) 7.7% 37.2% 55.1% ND $15.0M Sign & Close Ligand invested $18.0mm.
2025
Z Squared (Dogecoin mining co.)
Model this deal →
Coeptis Therapeutics (COEP)
ZSQR
Apr 2025 Apr 2026 ND ND ND ND ND ND Sign & Close Non-healthcare acquirer (Dogecoin/crypto mining). Coeptis spun out its biopharmaceutical operations concurrent with the merger; post-close renamed Z Squared Inc., ticker ZSQR.
2025
Protagenic Therapeutics
Phytanix Bio (PTIX)
PTIX
May 2025 Feb 2026 None (deal rescinded) — — — NA NA Terminated Reverse merger closed May 2025, then rescinded via Settlement/Unwind Agreement dated Feb 17, 2026. Protagenic returned all shares. PTIX now a clean shell seeking a new reverse merger.
2025
Viskase Companies (Affl Icahn Enterprises)
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Enzon Pharmaceuticals (ENZN)
ENZN
Jun 2025 Mar 2026 $25.0mm (AEP) 55% 40% 5% $40.9M ~$0.0M Sign & Close Related-party financing from Icahn affiliate AEP into Viskase.
2025
Zoar Labs (f/k/a Dr Ashleys)
Impact BioMedical (IBO)
PENDING (Zoar)
Jun 2025 NA (all-stock share exchange; no concurrent PIPE disclosed) 94.20% NA 5.80% ND ND Traditional Counterparty renamed, not changed: Dr Ashleys Limited is now Zoar Limited (PubCo) and Dr Ashleys Bio Labs is now Zoar Labs. API/intermediates manufacturer. Cayman PubCo; F-4 filed Sep 10, 2026. 1-for-12.62 IBO reverse split effective Sep 23, 2026. Lists on NYSE American.
2025
Clywedog Therapeutics
Barinthus Biotherapeutics (BRNS)
CLYD
Sep 2025 Sep 2026 None (all-stock) 66% NA 34% ND ND Traditional $27.0mm tender offer for Barinthus liquidity.
2025
Damora Therapeutics
Model this deal →
Galecto (GLTO)
DMRA
Nov 2025 Nov 2025 $285.0mm (Fairmount led; Viking Global, Venrock, Commodore, Janus, Wellington, RA, TCGX, Forbion, BB Biotech, Blackstone, Perceptive, Vestal Point, a16z) 36.1% 63.9% 0% ND $10.8M Sign & Close PIPE in Series C non-voting convertible preferred.
2025
Yarrow Bioscience
Model this deal →
VYNE Therapeutics (VYNE)
YARW
Dec 2025 Jul 2026 $200.0mm (RTW led; OrbiMed, Janus, venBio, Logos, LifeSci, Perceptive) 97% ND 3% $0.0M ~$15.0M–$16.0M Traditional
Cash Div
YES — $14.5-16.5M ($0.34-0.38/sh) pre-closing cash dividend to VYNE shareholders. Financing = ~$100.0mm Yarrow Series A at $4.94/sh + ~$100.0mm pre-closing PIPE.
2026
Faeth Therapeutics
Model this deal →
Sensei Biotherapeutics (SNSE)
FTH
Feb 2026 Feb 2026 $200.0mm (B Group, Balyasny, Columbia Threadneedle, Cormorant, Fairmount, Logos, RA, Vivo) 40.8% 54.3% 4.9% ~$18.0M ~$0.0M Sign & Close —
2026
PrimeGen US
DT Cloud Star Acquisition Corp. (DTSQ)
PENDING (PrimeGen US)
Feb 2026 ND ND ND ND ND ND SPAC Trust-account SPAC (DTSQ IPO Jul 2024, ~$69mm). Two-step: Redomestication Merger (Cayman parent into a Delaware purchaser), then Acquisition Merger. Dual-class outcome -- Company Class A/B holders receive Purchaser Class A/B respectively. Preclinical stem cell/exosome (triple-activated MSCs, acute liver failure). Outside date Oct 26, 2026, extendable 3 months. Minimum cash condition (amount not disclosed); 1,931,900 non-redemption warrants at $2.00 to non-redeeming holders.
2026
Candid Therapeutics
Model this deal →
Rallybio Corp (RLYB)
RLYB
Mar 2026 $505.5mm (Venrock, RA, Janus, T. Rowe Price, venBio, Viking Global, Cormorant, Foresite, Soleus, TCGX, Vivo) 57.56% 38.79% 3.65% $37.5M $10.0M Terminated
CVR
Terminated May 3, 2026: Candid took a UCB deal (up to $2.2B) via the Permitted Alternative Agreement carve-out; Rallybio received a $50mm termination fee plus $0.4mm expense reimbursement on May 4. Rallybio holders were to receive CVRs on REV102 sale proceeds and other legacy assets. Same shell later re-used for Avenzo (AVZO).
2026
Eos SENOLYTIX
Model this deal →
Pulmatrix (PULM)
MTXL
Mar 2026 $19.0mm 94% ND 6% $4.1M ND Pending Financing = $1.0mm PIPE + $18.0mm bridge.
2026
Korsana
Model this deal →
Cyclerion Therapeutics (CYCN)
KRSA
Apr 2026 Sep 2026 $380.0mm (Fairmount + Venrock co-led; General Atlantic, TCGX, Forbion, Wellington, Commodore, RA, RTW, Vivo, Janus, Foresite, JPM Life Sciences, SR One, Sanofi, Kalehua, Spruce Street) 40.8% 57.7% 1.5% $0.0M ~$9.9M Traditional
CVR
Exchange ratio pegged to $0 Cyclerion net cash at close. Acquirer % shown ex-financing so columns reconcile. Cyclerion holders receive CVRs on legacy assets.
2026
Obsidian Therapeutics
Model this deal →
Galera Therapeutics (GRTX)
OBX
Apr 2026 Aug 2026 $350.0mm (new: Balyasny, Caligan, Eventide, Nantahala, Octagon, Redmile, Spruce Street, Trails Edge; existing: Atlas, Deep Track, Foresite, Janus, Novo, RA, RTW, Wellington) 51.6% 47.2% 1.2% $1.8M ~$12.0M Traditional
CVR
Galera shareholders got CVRs for legacy assets. Split reflects the final closing exchange ratio (announcement: 53.2% / 45.0% / 1.8%).
2026
ACEA Pharma (WOS ACEA Therapeutics; Affl Scilex)
Phoenix Asia Holdings (PHOE)
PHOE
May 2026 NA (all-stock stock acquisition; no concurrent financing) 82% NA 18% ND ND SPAC/Other Non-healthcare shell: Phoenix Asia is a Hong Kong substructure/foundation contractor pivoting to pharma, same category as Coeptis and NOMAD. Seller is Scilex (SCLX), which holds ACEA Therapeutics as an indirect minority-owned subsidiary. Shell to be renamed ACEA Pharma, Inc. Lead asset abivertinib (Ph3 NSCLC).
2026
Orphai Therapeutics
Model this deal →
Quince Therapeutics (QNCX)
QNCX
May 2026 May 2026 $115.0mm 31.9% 61.2% 6.9% ND ND Sign & Close All-stock RM; combined co. keeps Quince Nasdaq listing. LAM-001 (inhaled rapamycin/mTOR) for rare pulmonary disease (PAH, PH-ILD). Upfront amount; plus up to $72.0mm via warrants (up to $187.0mm gross), in Series C non-voting convertible preferred.
2026
Mentari Therapeutics
Model this deal →
InMed Pharmaceuticals (INM)
INM
May 2026 $290.0mm (Fairmount led; Commodore, Deep Track, Janus, a16z, Venrock, Wellington, TCGX, Blackstone, BB Biotech, Farallon, RTW, Vivo, Perceptive, et al.) 29.67% 68.82% 1.51% ($3.4M) $10.0M Traditional
CVR
Combined co. renamed Mentari Therapeutics under a new ticker. PIPE includes $50.0mm of May 2026 convertible notes converting at closing. Parent Valuation $6.6mm at a $(3.4)mm net cash peg, adjusting dollar-for-dollar and capped at $10.0mm (excess cash goes to holders as a dividend). InMed holders get a CVR (and a potential dividend) on legacy-program monetization (INM-901, INM-089). Jul 22, 2026 amendment added $200.0mm at 152.80% of the original price, excluded from the exchange-ratio framework; post-amendment split Mentari side 98.85% / InMed 1.15%. Expected close 2H 2026.
2026
Avenzo Therapeutics
Model this deal →
Rallybio Corp (RLYB)
AVZO
Jun 2026 $215.0mm (Blackstone, T. Rowe Price, Vivo, OrbiMed, Foresite, NEA) 56.6% 40.6% 2.8% $0.0M $15.0M Pending
CVR
Cash Div
Follow-on to the terminated Candid deal, same shell. Rallybio distributes all net cash to legacy holders pre-close, plus CVRs on legacy assets. Expected close Q4 2026.
2026
Azora Therapeutics
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Adial Pharmaceuticals (ADIL)
ADIL
Jun 2026 Jun 2026 $32.0mm (Coastlands led) 51.0% 41.3% 7.7% ND ND Sign & Close All-stock acquisition; Adial pivots to AT177 (colon-targeted AhR agonist) for ulcerative colitis; legacy AD04 deprioritized. Upfront via pre-funded warrants; plus up to $32.0mm milestone tranche (up to $64.0mm gross).
2026
InnocsAI LLC
Model this deal →
Liminatus Pharma (LIMN)
LIMN
Jun 2026 Jul 2026 None disclosed (all-stock; no concurrent PIPE) 96.0% NA 4.0% ND ND Sign & Close
CVR
Split derived from the original 1.6B-share/$0.20 consideration vs. Liminatus's outstanding shares; later amended to a 19.99% common cap + non-voting preferred to close pre-vote. CVR = 20% of future net proceeds on acquired assets.
2026
NOMAD (AI Energy Co.)
Model this deal →
Lixte Biotechnology Holdings (LIXT)
NMAD
Jun 2026 Jul 2026 NA (all-stock share exchange; no PIPE into the shell) 77.7% NA 22.3% ~$16.5M ND Sign & Close Non-biotech suitor (utility-grade battery/BESS energy storage). Post-close renamed NOMAD Power Solutions, ticker NMAD.
2026
Remix Therapeutics
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Passage Bio (PASG)
RMTX
Jun 2026 $100.0mm (Decheng, Lynx1, Forge) 55.8% 37.2% 7% ND $20.0M Traditional
CVR
Passage Bio shareholders got non-transferable CVRs for pediatric gene therapy pipeline milestones
2026
Serapha Bio
Model this deal →
Boundless Bio (BBIO)
AATD
Jun 2026 $230.0mm (RA, RTW, Janus, Decheng, Vivo, Casdin, LifeSci, Logos, Balyasny, Eventide) 56.3% 40% 3.7% ~$0.0M ~$12.5M Traditional Financing = $138.0mm Serapha Series A + $92.0mm PIPE.
2026
Treeline Biosciences
Model this deal →
Standard BioTools (LAB)
TRLN
Jun 2026 None (all-stock) 84% NA 16% $450.0M ~$10.0M Traditional
CVR
1 CVR/share for legacy assets. >$900.0mm cash post-close.
2026
Talawar Therapeutics
Model this deal →
JATT II Acquisition Corp. (JATT)
TLWR
Jun 2026 $225.0mm (Access Biotech led; Bain, Deep Track, RA, Janus, Vianti, Farallon) 29.37% 52.71% 17.92% $60.0M $16.5M SPAC Trust-account SPAC ($60mm trust). No redemption backstop, unlike Oak Hill/RACC; $125mm minimum cash condition. JATT CEO Someit Sidhu also founded Khanda, which licensed TALA-125 to Talawar and is a major Talawar holder. Outside date Jan 31, 2027. PIPE at $10.00/sh.
2026
Cortigent, Inc. (WOS Vivani Medical)
Model this deal →
ClearOne, Inc. (CLRO)
CRGT
Jul 2026 $10.0–$15.0mm 59.4%–67.5% ND 12.7%–14.4% ND ND Pending Cortigent = brain-computer interface (BCI) / neurostimulation tech (from Second Sight Medical Products). Closing conditioned on stockholder approvals, completion of $10-15mm financing, minimum net cash requirement (threshold not disclosed), continued Nasdaq listing. Concurrent S-1 financing, not yet closed.
2026
GH Power Inc.
Model this deal →
Matinas BioPharma Holdings (MTNB)
MTNB
Jul 2026 $15.0mm 86.3% 5.2% 8.5% $0.0M $24.7M Traditional Cross-border: Ontario Pubco holds both companies; Matinas sold its biotech subsidiary (MAT2203, LNC platform) to Azurity separately for up to $21.5mm. Requires both companies' shareholder votes, Ontario court approval, and F-4 effectiveness. Expected close Q4 2026. GH Power raise; $15.0mm is the closing-condition minimum, actual amount not yet fixed.
2026
Avere Therapeutics
Model this deal →
NextCure, Inc. (NXTC)
AVRX
Jul 2026 $320.0mm (Fairmount, Hansoh, et al.) 43.0% 55.1% 1.9% $0.0M $11.0M Traditional
CVR
All-stock merger; combined company renamed Avere Therapeutics (AVRX). NextCure holders receive CVRs on legacy assets (90% of proceeds, 2-yr term). Expected close Q3 2026. ~$251.0mm of the PIPE via convertible-note exchange.
2026
Lōkahi Therapeutics
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Glucotrack, Inc. (GCTK)
GCTK
Jul 2026 Jul 2026 $4.5mm 90.0% NA 10.0% ND ND Sign & Close Signed and closed same day. Glucotrack keeps its own name and GCTK ticker; Lōkahi becomes the operating and controlling business. Erik Emerson (Lōkahi) becomes CEO; Glucotrack's CBGM diabetes business moves to an Operating Sub under Paul Goode. Glucotrack was before a Nasdaq Hearings Panel (Jun 18, 2026) on minimum bid and stockholders' equity compliance; ran a 1-for-15 reverse split Aug 31. Bridge financing: senior secured convertible notes, $5.7mm face, 22% OID, 8% coupon, maturing Apr 2027; a separate post-closing private placement (amount not disclosed) is permitted.
2026
Kira Pharmaceuticals
Model this deal →
Jasper Therapeutics (JSPR)
JSPR
Jul 2026 Jul 2026 $132.0mm (Affinity + Ikarian co-led; Columbia Threadneedle, Sirenia, Brahma, Balyasny, SilverArc, Squadron, Nazare, Mirador, et al.) 49.9% 43.5% 6.7% $0.0M $20.3M Sign & Close
CVR
Merger completed pre-vote via non-voting convertible preferred (19.9% common cap), same structure as Liminatus. Ticker stays JSPR. CVR: $30mm aggregate tied to a briquilimab priority review voucher by Dec 31, 2028, payable only on monetization or acquisition.
2026
Scancell (AIM: SCLP)
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Neuphoria Therapeutics Inc. (Nasdaq: NEUP; renamed Scancell, new ticker SCLT)
SCLT
Jul 2026 $54.1mm 85.5% ND 14.5% $10.0M $14.6M Traditional
CVR
Foreign (AIM) uplisting via Nasdaq merger. Scancell legally acquirer/parent but economically the private side. Net cash $10mm is a closing condition (not a true-up peg), not a fixed peg. Expected close Q4 2026. Equity = $39.1mm private placement + $12.0mm UK placing + $3.0mm retail offer; plus a $25.0mm BlackRock debt facility.
2026
Oak Hill Bio (OHB Pediatrics Ltd.)
Model this deal →
Research Alliance Corporation III (Nasdaq: RACC)
OAKH
Jul 2026 $100.0mm (RA led; Balyasny, Janus, KCap, venBio, ADAR1, Affinity, Ally Bridge, BVF, Great Point, Logos, SilverArc, Trails Edge) 45.3% 28.9% 25.8% $75.0M $16.0M SPAC Classic trust-account SPAC (RA Capital-sponsored), unlike most 'shell' deals in this tracker. Any RACC trust redemptions are backstopped dollar-for-dollar by RA Capital. Combined co. trades as OAKH; developing rugonersen (ASO) for Angelman syndrome, Phase 3 ongoing. RA funded $45.0mm via a SAFE at signing; balance via PIPE at $10.00/sh at closing.
2026
Caldera Therapeutics
Model this deal →
Synlogic, Inc. (SYBX)
CALD
Jul 2026 $278.0mm (Bain, TCGX, Atlas, venBio, Omega, Blackstone, LAV, Wellington, Janus, Sirenia, Vivo, et al.) 62.8% 34.9% 2.3% $6.0M $12.0M Traditional Both companies become subsidiaries of a newly formed holdco (Sonic Holdco, Inc.), same structure as Matinas/GH Power. Requires both companies' shareholder votes and an effective SEC registration statement. Expected close early 2027.
2026
Vidya Therapeutics
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Processa Pharmaceuticals (PCSA)
PCSA
Jul 2026 Jul 2026 $200.0mm (Bain, Janus, RA, SilverArc, ADAR1, Cormorant, Integral Health, Marshall Wace, Octagon, Soleus, et al.) 46.0% 52.6% 0.9% $0.0M $3.4M Sign & Close Unlike most deals here, Processa keeps its own name/ticker -- Vidya is absorbed under Processa's continuing corporate identity. Legacy Processa assets (PCS499, PCS12852) continue in the combined co. Preferred conversion requires a later stockholder vote. PIPE oversubscribed vs. a $175.0mm contractual floor.
2026
Cy Biopharma
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Ensysce Biosciences (ENSC)
ENSC
Aug 2026 Aug 2026 $21.5mm (Ally Bridge led; Perceptive, Dellora, Ikarian, Adage) 74.94% 17.49% 7.57% ND ND Sign & Close Fixed-share-consideration deal with no stated net-cash peg (net cash/premium ND). Split is per the company's amended 8-K/A (ex-Milestone Closing); the original 8-K showed 73.86% for Cy and a $101.4mm value, which the company later corrected. Combined fully diluted equity value ~$122.9mm at the $0.32179 PIPE price. The 'third party' is 3i, LP, whose Series B and warrants were converted at closing. Post-close cash ~$31mm net of transaction expenses vs. $38.6mm gross new money. Cy Biopharma founder James Morrison becomes President and joins the board. Preferred conversion awaits a stockholder vote. Initial tranche $21.5mm at $0.32179/sh as-converted; milestone tranche up to $21.5mm more at $0.40224/sh (~$43.0mm total).
2026
Redx Pharma
Model this deal →
Skye Bioscience (SKYE)
PENDING (Fibrx Therapeutics, Inc.)
Aug 2026 $103.9mm 46.17% 48.45% 5.38% $2.0M $12.5M Traditional
CVR
Redx's second reverse-merger attempt -- first (with Jounce, 2023) is tracked separately as terminated. Redx went private between the two attempts. Requires UK court sanction of a Scheme of Arrangement plus both companies' shareholder votes. Skye also doing an unrelated 1-for-8 reverse split (Nasdaq compliance) effective Aug 24, 2026. Termination fee: 3% of combined co. valuation. Financing = $67.9mm concurrent financing + $36.0mm Redx Series A; up to $22.0mm more via an undrawn equity line.
2026
Slate Medicines
Model this deal →
Fulcrum Therapeutics (FULC)
SLTE
Aug 2026 $245.0mm (Frazier led; Forbion, RA, Deep Track, Foresite, OrbiMed, RTW, Mingxin) 55.9% 39.1% 5.0% $20.3M $11.0M Traditional
Cash Div
Fulcrum discontinued its lead sickle-cell candidate (pociredir) in Jun 2026 after FDA raised cancer-risk concerns, cut 85% of staff, and ran a strategic review (Leerink advising) before this deal. Fulcrum pays a ~$270mm cash dividend to its own legacy shareholders pre-close -- no CVR, as pociredir has no viable regulatory path. Wedbush advised Slate.
2026
Ambros Therapeutics
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Werewolf Therapeutics (HOWL)
AMBX
Aug 2026 $150.0mm (RA + Janus co-led; Aberdeen, Adage, ADAR1, Affinity, Arkin Bio, Balyasny, Enavate, SilverArc, Sphera, Woodline) 71.7% 21.5% 6.8% $30.0M $17.5M Traditional
CVR
Werewolf ran a strategic review (Piper Sandler advising) after cutting 64% of staff in Feb 2026 amid going-concern risk. CVR ties to Werewolf's own legacy INDUKINE programs (WTX-124, WTX-330). Asymmetric termination fees: $20.0mm from Ambros, $1.9mm from Werewolf. Support agreements cover ~71.3% of Ambros shares, ~1.4% of Werewolf shares. Expected close Q1 2027. PIPE closing condition requires a $100.0mm minimum.
2026
Marea Therapeutics
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Lisata Therapeutics (LSTA)
LSTA
Sep 2026 Sep 2026 $225.0mm (RA, Forbion, Third Rock, Alpha Wave, Perceptive, Sofinnova, Omega, Surveyor (Citadel), Columbia Threadneedle, Nantahala, Affinity, venBio, Rock Springs) 59.54% 38.07% 2.39% ($3.9M) $18.0M Sign & Close Lisata keeps its name and LSTA ticker; Marea takes control and pivots the company from oncology to cardioendocrine. Follows the collapse of Lisata's Kuva Labs take-private (terminated, 72% workforce cut). Rare negative net cash: -$3.85mm per the Parent Net Cash Certificate. Series C conversion requires a later stockholder vote. PIPE: 150,867.995 Series C preferred at ~$1,491.37/sh (~$1.4914 as-converted).
2026
North Immunology
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Aethlon Medical (AEMD)
NRTX
Sep 2026 $180.0mm (Bain, Janus, Deep Track, Longitude, Soleus, Invus, Sirenia, Farallon, Adage, TCGX) 43.30% 51.95% 4.75% $0.0M $16.5M Traditional
CVR
North founded and incubated by ADAR1 Capital Management. Aethlon holders receive CVRs on the legacy Hemopurifier business. Aethlon's 4.75% is reduced if its net cash at closing falls below $0. Expected close Q1 2027. Includes ~$34.0mm conversion of North convertible notes.
2026
Velaris Therapeutics
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Alaunos Therapeutics (TCRT)
TCRT
Oct 2026 Oct 2026 $350.0mm (Fairmount led; Venrock, T. Rowe Price, Wellington, Janus, Access Biotech, BB Biotech, Perceptive, Sirenia, ADAR1) 36.01% 63.01% 0.98% ND $15.0M Sign & Close Fairmount/Paragon NewCo #9 (PAH: ActRIIA-Fc ligand traps + anti-PDGF-B). Signed and closed same day; preferred conversion awaits a later stockholder vote. Legacy Alaunos holders keep ~1%, among the smallest shell stakes in the tracker (cf. Vidya/Processa ~0.9%). Financing upsized from a $250.0mm minimum condition to $350.0mm. Paragon can reclaim the licensed IP if stockholders' equity does not exceed $200mm at the end of the second full quarter after closing. Company to be renamed Velaris Therapeutics; new ticker TBD.

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